σύνδρομο Meniere

Unfortunately, there are certain conditions that can affect a patient’s mental state and quality of life on multiple levels. One such condition is Meniere’s syndrome. The hearing loss and related issues it causes are not just physical disturbances, but often deeply distressing and debilitating experiences. Many patients also develop anxiety, irritability, or even depression as they struggle to adapt to an unpredictable and constantly changing situation. Quality of life is directly impacted—not only in practical terms, but also in self-esteem, social engagement, and overall mental health.

What is Meniere’s syndrome?

Meniere’s syndrome is a chronic and particularly complex disorder of the inner ear that affects both hearing and balance, significantly impacting patients’ quality of life. The disease is characterized by recurrent episodes of intense rotational vertigo, tinnitus (ringing or buzzing in the ears), a feeling of pressure or fullness in one or both ears, and often temporary or progressive hearing loss. These episodes usually occur without warning and can last from a few minutes to several hours, with the average duration being between two and four hours.

After an episode, patients often feel exhausted and experience a strong need for rest and sleep due to both physical and neurological strain. In some people, episodes are frequent, while others may go years between occurrences. Notably, about 0.2% of the general population is affected by the condition, with most cases involving only one ear (about 2 out of 3), although in one-third of cases both ears may eventually be affected.

Causes and pathogenesis of Meniere’s syndrome

Despite extensive research, the exact cause of the syndrome remains unclear. The dominant theory suggests it is related to increased pressure of the endolymphatic fluid in the inner ear (endolymphatic hydrops). When the volume or composition of this fluid, which surrounds the inner ear’s sensory cells, is disturbed, it leads to mechanical and functional dysfunction, causing the typical symptoms. Contributing factors may include heredity, viral infections, immune disorders, allergies, head trauma, and migraines. Hearing loss tends to be progressive, and over time may lead to permanent hearing impairment in some patients.

Symptoms caused by Meniere’s syndrome

Meniere’s syndrome symptoms typically occur in flare-ups, causing sudden deterioration in daily functioning. The most distinctive symptom is vertigo—a sensation that either the surroundings or the person is spinning—often accompanied by nausea, vomiting, imbalance, and fear of falling. Vertigo can last from minutes to hours and is often debilitating. At the same time, patients frequently report a feeling of pressure, fullness, or heaviness in the ear, which may precede or accompany the episode. Tinnitus, described as buzzing, whistling, or ringing in the ear, is common and often persists between episodes.

Hearing loss is initially temporary and mostly affects low frequencies, but as the disease progresses, it tends to become permanent and may worsen. In more advanced stages, patients may experience sound distortion (paracusis) or increased sensitivity to certain sounds. Additionally, it is not uncommon for patients to experience a persistent feeling of lightheadedness even between attacks, which affects daily activities and self-confidence. The intensity, frequency, and combination of symptoms vary greatly between individuals, making the clinical presentation highly variable and personalized.

Diagnosis of the disease

Diagnosis of Meniere’s syndrome relies primarily on patient history and clinical symptom presentation, as no single test definitively confirms the condition. The combination of rotational vertigo, hearing loss, tinnitus, and a feeling of fullness in the ear is key for diagnosis. Audiological tests, such as an audiogram (to measure the type and degree of hearing loss), and electronystagmography (to evaluate the vestibular system), support the diagnosis. MRI may be used in some cases to rule out other conditions with similar symptoms, such as acoustic neuroma or multiple sclerosis.

Management during and between episodes

Treatment focuses on symptom relief, as there is currently no definitive cure. During an episode, the patient should lie down with eyes open, fixed on a stationary point, and avoid drinking fluids if experiencing nausea. After the vertigo subsides, gradual movement and adequate rest are needed. If nausea or vomiting is severe, medication may be prescribed. Between episodes, several measures are used to reduce their frequency and intensity. Diuretics are commonly prescribed to lower inner ear fluid pressure, and in more severe cases, oral or injectable steroids and vestibular suppressants may be used. In some cases, calcium channel blockers or, more rarely, immunosuppressants may be added.

Diet and Meniere’s syndrome

Diet plays an important role in managing the disease, though it is not a cure-all. The goal is to stabilize the volume and composition of body fluids to prevent fluctuations affecting the inner ear. Recommended strategies include reducing salt intake (less than 1 gram per day), avoiding caffeine (coffee, tea, chocolate), alcohol, and monosodium glutamate (MSG), as these can worsen fluid pressure and symptoms. It’s also important to maintain consistent fluid intake and avoid meals high in sugar or salt, to prevent sudden changes in osmolality and fluid volume in the inner ear. Diet should always be tailored to the individual patient’s needs.

Surgical and interventional treatment

When conservative treatments fail and vertigo episodes are severe and frequent, interventional options are considered. One method involves intratympanic injection of gentamicin, which destroys vestibular cells in the affected ear, thereby reducing vertigo without affecting the other ear. Alternatively, vestibular nerve section or labyrinthectomy may be performed to permanently eliminate vertigo, although these procedures carry the risk of worsening balance or hearing.

Impact on daily life and psychological dimension

Meniere’s syndrome can deeply affect daily life, particularly due to the unpredictable nature of episodes. Patients may need to adapt their environment and habits for safety, such as keeping a light on at night or keeping hallways clear. It is crucial for those close to the patient to understand the condition and offer support during episodes. The psychological burden from anxiety over attacks, chronic hearing loss, and tinnitus is significant and should not be overlooked. Many patients experience depression or anxiety and may benefit from psychological or pharmaceutical support.

Although Meniere’s syndrome has no definitive cure, proper and consistent management can help patients experience fewer and milder episodes, preserving their hearing and balance as much as possible. Awareness, adherence to treatment, and adopting a healthy lifestyle form the foundation for a better quality of life, says ENT Surgeon in Athens Dr. Olga Papadopoulou.